Neonatal Ventilation And Lung Protection  - A preemie is supplied with oxygen

Neonatal Ventilation And Lung Protection

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Neonatal ventilation is an important part of the care delivered in the neonatal intensive care unit (NICU). But ventilation of preemies and neonates is a substantial challenge for even the most experienced caregiver: Respiratory insufficiency remains one of the major causes of neonatal mortality. Despite the introduction of sophisticated conventional ventilation, there are still some neonates who cannot be adequately ventilated. 

Immature lungs and underdeveloped breathing require extremely gentle ventilation and advanced technology. The aim of any ventilation strategy is therefore to support the premature infant’s respiratory system without inducing damage to the lung or the brain. Our ventilation strategies accompany neonates and care givers from the beginning to the end of respiratory challenges: It is our aim to help you prevent or minimise pulmonary injury, impairment and work of breathing, whilst optimising comfort and allowing your little patients to grow safely. 

Improve your outcome with volume guarantee

Volume guarantee is a mode of ventilation used for measuring tidal volumes and monitoring changes in lung characteristics with sophisticated software algorithms. It has been designed to combine the advantages of both pressure-limited ventilation and volume-controlled ventilation. Clinical evidence has shown that babies ventilated with volume guarantee are more likely to survive – free of lung damage and chronic diseases. These benefits can also attribute to cost reductions in the NICU.

Downloads to enrich your knowledge

Volume controlled ventilation for neonates booklet
Volume Guarantee for Neonates

Read more about new approaches in volume targeted ventilation for newborn babies.

Download booklet

Neonatal ventilation interview with Prof. Martin Keszler
Prof. Martin Keszler on Neonatal Ventilation

Prof. Martin Keszler talks about how neonatal ventilation has progressed throughout the years and how volume guarantee can support a positive outcome of neonatal ventilation.

Download interview

Volume guarantee case study
Case study: Volume Guarantee in Seattle

In this case study, you will read about the initiation and ongoing clinical management of infants supported by volume guarantee.

Download case study

Volume guarantee ventilation in neonates booklet
Ventilation Insights: Volume Guarantee Ventilation

The aim of any ventilation strategy is to support the neonate‘s respiratory system without inducing damage to the lung or the brain. Volume Guarantee ventilation supports stabilisation of the infant and gentle respiratory treatment with a more stable minute ventilation. Learn more in our Ventilation Insights on how Volume Guarantee ventilation helps to improve patient outcome.

Download ventilation insights

Volume guarantee literature list
Literature list: Volume Guarantee

Want to read more about clinical studies, cases and reviews on volume guarantee? Take a look at our literature list.

Download literature list

High-Frequency Oscillatory Ventilation (HFOV) for Neonates

HFOV is a mode of ventilation which has been in clinical use for over thirty years. In many hospitals around the world, HFOV is now an established first-intention ventilation approach for respiratory disease. HFOV is used to treat diseases such as respiratory distress syndrome, pneumonia, meconium aspiration syndrome, persistent pulmonary hypertension of the newborn and lung hypoplasia – more successfully and more gently than conventional ventilation.

Watch our webinar: HFOV in the preterm infant

The webinar “High Frequency Oscillatory Ventilation in Preterm Infants” with Prof. Giovanni Vento, will help you become familiar with the clinical application of HFOV – combining volume guarantee with HFOV, as well as troubleshooting and recruitment strategies.

Watch our webinar: High-Frequency Ventilation

This webinar focuses on High Frequency Oscillatory Ventilation (HFOV). Particular emphasis is placed on understanding the basis for practical application approaches that maximise the potential benefits and minimise the risk of adverse outcomes of HFOV therapy. Additionally, theoretical background information for lung protective and efficient application are given. A step-by-step approach for the application of HFOV with the Babylog VN500 is presented, alongside clinical recommendations and guidance on how to set and optimise therapy with HFO.

Recommended downloads

Theoretical and practical applications of HFOV booklet
Theoretical and practical applications of HFOV

The booklet 'High-Frequency Oscillatory Ventilation' written by Prof. Jane Pillow aims both to help less experienced clinicians become familiar with high-frequency oscillation, whilst also providing additional detail to enhance the understanding of more experienced HFOV users.

Download booklet

High frequency ventilation oscillation booklet
Ventilation Insights: High-Frequency Oscillation

High-Frequency Oscillatory Ventilation (HFOV) is a comprehensive ventilator strategy applied as priori and rescue ventilator modality in order to improve pulmonary gas exchange. It offers opportunities for lung protective ventilation whilst minimising rheotrauma. Learn more in our Ventilation Insights on how HFOV helps to improve patient outcome.

Download ventilation insights


New: Background and Clinical Applications of MMV

Our new booklet outlines the background and clinical applications of MMV in neonates to enable you to maximise the potential benefits and to ensure its safe application.

Mandatory Minute Ventilation (MMV)

Mandatory Minute Ventilation (MMV) is a relatively simple closed-loop mode of ventilation, whereby the ventilator delivers pressure-limited, volume-targeted mandatory breaths when the minute volume (generated by pressure supported spontaneous breaths) falls below a target minimum Minute Volume (MV). It gives you the possibility to control your patient’s ventilation, whilst safeguarding on a minimum minute ventilation level. In addition, it can be considered a safe weaning strategy as it combines frequency adaptation and pressure adaptation in one mode and adapts to the individual patient needs. Furthermore, it adapts safely for leakage for trigger sensitivity and compensates for leakage in volume guarantee.

Webinar: Mandatory Minute Ventilation with Prof. Jane Pillow

Our webinar “Mandatory Minute Ventilation” will help you become more familiar with the theory, clinical application and operating principle of MMV.

  • Understanding how MMV works
  • Theoretical benefits and risks of MMV
  • Clinical application of MMV in neonates
  • PC-MMV and Volume Guarantee operating principle

Recommended downloads

Mandatory minute ventilation in premature infants booklet
Ventilation Insights: MMV in Premature Infants

The start of ventilation therapy is always the start of a weaning process. To prevent chronic lung diseases such as BPD, it is essential to directly help the infant to regain their own respiratory drive. Mandatory Minute Ventilation 'closes the loop' in the weaning process. Learn more in our Ventilation Insights on how Mandatory Minute Ventilation helps to improve patient outcome.

Download ventilation insights

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