Patient-ventilator asynchrony is a common but often unrecognized and undertreated problem in non-invasive ventilation (NIV) that may occur in up to 25 % of ventilated patients¹. It is mostly related to missed triggers and delayed cycling associated with leaks².

• A relevant indicator of a ventilator’s efficiency is the inspiratory delay, which is the time needed for the ventilator to reach positive pressure in the patient’s airway from the start of inspiratory effort. A long inspiratory delay significantly increases the patient’s work of breathing³. Savina 300 NIV very quick response to triggering and its pressurization capacity reduces the patients work of breathing and discomfort resulting in a remarkably low asynchrony index⁴.
• Leakage occurs not only during inspiration but also during expiration. If expiratory leakage cannot be measured accurately, it results in inaccurate compensation of targeted tidal volumes³. Savina 300 devices effectively compensate air leaks and deliver the prescribed tidal volume regardless air leak or inspiratory effort⁴.
• Patients in pressure support ventilation utilizing a preselected inspiratory cycling criteria (termination) may experience expiratory asynchrony⁵. Furthermore, studies show that the cycling setting must be individualized, since factors like e.g., response time of the respiratory system and breathing frequency will probably affect how a patient responds⁶. In all Savina 300 devices the inspiratory termination can be individually adjusted to the patient’s lung properties and breathing pattern and thus achieve a better adaptation.
  

A comparison of high-flow nasal oxygen delivery vs Venturi mask oxygen therapy has shown improvements in oxygenation, comfort, and clinical outcomes. When using a high-flow nasal O₂ system, this study demonstrated a reduced need for non-invasive ventilation by approximately 80 %, less episodes of O₂ desaturation by an estimated 66 %, less need for reintubation by approximately 80 %, and a reduced length of stay in the ICU by an approximate average of 1.3 days⁷

• High-Flow Oxygen Therapy supports recovery after extubation and non-invasive ventilation: flushing of anatomical dead space thereby functionally reducing dead space and improving respiratory efficiency⁸
• Time management for the caregiver is streamlined as one device can remain at the bedside of the patient simply by changing the patient-circuit interface: complete set-up for High-Flow nasal O₂-therapy
• Enhanced patient comfort due to the soft nasal prongs which ensures a comfortable fit. Skin lesions and other undesirable effects associated with masks are reduced⁹. Heating and humidification of the gas mix further improves both patient tolerance and therapeutic efficacy^{10, 11, 12}

Operate the Savina 300 NIV ventilator with confidence in any situation, thereby lower education times and help to avoid human errors.

• The design of a ventilator can have a significant impact on patient safety and user experience due to poor user interfaces, or difficulties with the physical setup of the device. Savina 300 devices are easy to use. All helpful options can be found directly on the main screen. The display is easy to configure, and the menu is very intuitive¹³. This confidence in use may also help to reduce training time.
• The automatic device check guides the user through the respective test steps in the form of a question/answer dialog supporting quick operational readiness.
• Alarms are signalled optically and acoustically. The alarm light flashes in the colour of the corresponding alarm priority as well as the initiating parameter and the corresponding measured alarm value. The alarm with the highest priority is signalled acoustically. This intelligent alarm handling allows quick response to patient alarm situations.
• Cleaning, disinfection, and sterilization are the backbone of infection prevention and control in hospitals and other health care facilities. It can increase patient as well as caregiver safety. At the same time, the cleaning process should be kept as effective as possible. The Savina 300 devices are designed with smooth, clear surfaces and rounded profiles to ensure easy and effective cleaning. The surfaces are treatable with the same validated disinfectants as other Dräger devices due to its material resistance.
  

The Savina 300 NIV compresses ambient air for the breathing gas* allowing the device to operate independently from the central gas supply.

• Built-in-turbines are able to generate high flows which are required for non-invasive ventilation and to compensate even big leaks which are typical in non-invasive ventilation. Savina 300 devices with its built-in-turbine and rapid response time is capable to generate not only a high peak flow but a continuous high flow of up to 250 l/min.
  
• Due to the turbine, Savina 300 devices operate independently from a central gas supply and the built-in and external batteries allow for five hours of independent ventilation, e.g., during intrahospital transport.